Q04771 (ACVR1)

Overview
Predicted structure (AF):
AF-Q04771-F1-model_v4
Uniprot entry:
Q04771
Gene:
ACVR1
Protein length:
509 residues
Mutations found:
9670
Benign based on D2Deep prediction:
5151 out of 9670 mutations
Pathogenic based on D2Deep prediction:
4519 out of 9670 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9670 mutations across 509 unique positions. There are 5151 benign and 4519 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 C 3 16 19 0.862 0.588 View mutations
352 I 0 19 19 0.999 0.712 View mutations
353 A 0 19 19 1.000 0.724 View mutations
354 D 0 19 19 1.000 0.752 View mutations
355 L 0 19 19 0.983 0.652 View mutations
356 G 0 19 19 1.000 0.743 View mutations
357 L 0 19 19 1.000 0.743 View mutations
358 A 0 19 19 1.000 0.727 View mutations
359 V 0 19 19 1.000 0.729 View mutations
360 M 13 6 19 0.282 0.467 View mutations
361 H 4 15 19 0.822 0.543 View mutations
362 S 10 9 19 0.462 0.500 View mutations
363 Q 1 18 19 0.917 0.446 View mutations
364 S 10 9 19 0.506 0.436 View mutations
365 T 14 5 19 0.305 0.436 View mutations
366 N 14 5 19 0.251 0.417 View mutations
367 Q 12 7 19 0.432 0.440 View mutations
368 L 1 18 19 0.939 0.592 View mutations
369 D 14 5 19 0.323 0.458 View mutations
370 V 16 3 19 0.145 0.447 View mutations
371 G 13 6 19 0.321 0.465 View mutations
372 N 17 2 19 0.118 0.475 View mutations
373 N 0 19 19 1.000 0.643 View mutations
374 P 0 19 19 0.942 0.685 View mutations
375 R 1 18 19 0.946 0.763 View mutations