Q04771 (ACVR1)

Overview
Predicted structure (AF):
AF-Q04771-F1-model_v4
Uniprot entry:
Q04771
Gene:
ACVR1
Protein length:
509 residues
Mutations found:
9670
Benign based on D2Deep prediction:
5151 out of 9670 mutations
Pathogenic based on D2Deep prediction:
4519 out of 9670 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9670 mutations across 509 unique positions. There are 5151 benign and 4519 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 Q 18 1 19 0.073 0.642 View mutations
77 G 17 2 19 0.108 0.626 View mutations
78 K 10 9 19 0.494 0.461 View mutations
79 M 15 4 19 0.256 0.492 View mutations
80 T 11 8 19 0.408 0.448 View mutations
81 C 0 19 19 1.000 0.447 View mutations
82 K 13 6 19 0.369 0.490 View mutations
83 T 17 2 19 0.144 0.472 View mutations
84 P 18 1 19 0.030 0.561 View mutations
85 P 18 1 19 0.055 0.530 View mutations
86 S 19 0 19 0.010 0.620 View mutations
87 P 19 0 19 0.062 0.673 View mutations
88 G 18 1 19 0.063 0.646 View mutations
89 Q 18 1 19 0.041 0.583 View mutations
90 A 19 0 19 0.001 0.608 View mutations
91 V 19 0 19 0.021 0.478 View mutations
92 E 19 0 19 0.000 0.584 View mutations
93 C 10 9 19 0.464 0.426 View mutations
94 C 3 16 19 0.757 0.549 View mutations
95 Q 16 3 19 0.249 0.540 View mutations
96 G 7 12 19 0.574 0.430 View mutations
97 D 18 1 19 0.062 0.568 View mutations
98 W 19 0 19 0.022 0.466 View mutations
99 C 18 1 19 0.134 0.457 View mutations
100 N 10 9 19 0.452 0.443 View mutations