Q04771 (ACVR1)

Overview
Predicted structure (AF):
AF-Q04771-F1-model_v4
Uniprot entry:
Q04771
Gene:
ACVR1
Protein length:
509 residues
Mutations found:
9670
Benign based on D2Deep prediction:
5151 out of 9670 mutations
Pathogenic based on D2Deep prediction:
4519 out of 9670 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9670 mutations across 509 unique positions. There are 5151 benign and 4519 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 R 18 1 19 0.074 0.667 View mutations
102 N 11 8 19 0.386 0.476 View mutations
103 I 17 2 19 0.170 0.577 View mutations
104 T 10 9 19 0.486 0.470 View mutations
105 A 14 5 19 0.327 0.549 View mutations
106 Q 19 0 19 0.014 0.745 View mutations
107 L 19 0 19 0.001 0.652 View mutations
108 P 18 1 19 0.059 0.736 View mutations
109 T 19 0 19 0.000 0.835 View mutations
110 K 19 0 19 0.000 0.853 View mutations
111 G 19 0 19 0.002 0.831 View mutations
112 K 19 0 19 0.001 0.870 View mutations
113 S 19 0 19 0.000 0.862 View mutations
114 F 19 0 19 0.005 0.860 View mutations
115 P 19 0 19 0.002 0.871 View mutations
116 G 19 0 19 0.006 0.892 View mutations
117 T 18 1 19 0.070 0.847 View mutations
118 Q 19 0 19 0.004 0.898 View mutations
119 N 19 0 19 0.002 0.867 View mutations
120 F 19 0 19 0.001 0.883 View mutations
121 H 19 0 19 0.011 0.912 View mutations
122 L 18 1 19 0.051 0.872 View mutations
123 E 19 0 19 0.013 0.862 View mutations
124 V 19 0 19 0.001 0.822 View mutations
125 G 19 0 19 0.011 0.912 View mutations