Q04771 (ACVR1)

Overview
Predicted structure (AF):
AF-Q04771-F1-model_v4
Uniprot entry:
Q04771
Gene:
ACVR1
Protein length:
509 residues
Mutations found:
9670
Benign based on D2Deep prediction:
5151 out of 9670 mutations
Pathogenic based on D2Deep prediction:
4519 out of 9670 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9670 mutations across 509 unique positions. There are 5151 benign and 4519 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 L 19 0 19 0.003 0.897 View mutations
127 I 18 1 19 0.099 0.853 View mutations
128 I 12 7 19 0.394 0.590 View mutations
129 L 19 0 19 0.037 0.864 View mutations
130 S 15 4 19 0.215 0.717 View mutations
131 V 13 6 19 0.347 0.611 View mutations
132 V 10 9 19 0.533 0.497 View mutations
133 F 18 1 19 0.119 0.742 View mutations
134 A 11 8 19 0.405 0.517 View mutations
135 V 19 0 19 0.010 0.730 View mutations
136 C 19 0 19 0.030 0.785 View mutations
137 L 10 9 19 0.472 0.488 View mutations
138 L 11 8 19 0.449 0.507 View mutations
139 A 16 3 19 0.143 0.651 View mutations
140 C 17 2 19 0.123 0.677 View mutations
141 L 12 7 19 0.338 0.527 View mutations
142 L 19 0 19 0.037 0.709 View mutations
143 G 19 0 19 0.000 0.671 View mutations
144 V 15 4 19 0.262 0.565 View mutations
145 A 19 0 19 0.026 0.674 View mutations
146 L 19 0 19 0.004 0.679 View mutations
147 R 18 1 19 0.074 0.665 View mutations
148 K 19 0 19 0.001 0.702 View mutations
149 F 19 0 19 0.002 0.705 View mutations
150 K 19 0 19 0.000 0.726 View mutations