B9A064 (IGLL5)

Overview
Predicted structure (AF):
AF-B9A064-F1-model_v4
Uniprot entry:
B9A064
Gene:
IGLL5
Protein length:
214 residues
Mutations found:
4065
Benign based on D2Deep prediction:
3327 out of 4065 mutations
Pathogenic based on D2Deep prediction:
738 out of 4065 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4065 mutations across 214 unique positions. There are 3327 benign and 738 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 E 4 15 19 0.689 0.501 View mutations
127 L 13 6 19 0.324 0.460 View mutations
128 Q 9 10 19 0.508 0.437 View mutations
129 A 18 1 19 0.050 0.375 View mutations
130 N 10 9 19 0.555 0.423 View mutations
131 K 7 12 19 0.586 0.528 View mutations
132 A 3 16 19 0.803 0.704 View mutations
133 T 2 17 19 0.794 0.694 View mutations
134 L 2 17 19 0.877 0.779 View mutations
135 V 8 11 19 0.585 0.564 View mutations
136 C 13 6 19 0.334 0.334 View mutations
137 L 5 14 19 0.734 0.710 View mutations
138 I 17 2 19 0.157 0.282 View mutations
139 S 5 14 19 0.652 0.671 View mutations
140 D 2 17 19 0.885 0.804 View mutations
141 F 5 14 19 0.688 0.694 View mutations
142 Y 19 0 19 0.019 0.243 View mutations
143 P 19 0 19 0.000 0.256 View mutations
144 G 18 1 19 0.045 0.356 View mutations
145 A 19 0 19 0.006 0.429 View mutations
146 V 19 0 19 0.000 0.318 View mutations
147 T 17 2 19 0.096 0.467 View mutations
148 V 19 0 19 0.000 0.227 View mutations
149 A 19 0 19 0.005 0.338 View mutations
150 W 19 0 19 0.000 0.251 View mutations