B9A064 (IGLL5)

Overview
Predicted structure (AF):
AF-B9A064-F1-model_v4
Uniprot entry:
B9A064
Gene:
IGLL5
Protein length:
214 residues
Mutations found:
4065
Benign based on D2Deep prediction:
3327 out of 4065 mutations
Pathogenic based on D2Deep prediction:
738 out of 4065 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4065 mutations across 214 unique positions. There are 3327 benign and 738 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 K 18 1 19 0.123 0.402 View mutations
152 A 16 3 19 0.183 0.495 View mutations
153 D 15 4 19 0.244 0.470 View mutations
154 G 16 3 19 0.146 0.325 View mutations
155 S 10 9 19 0.473 0.435 View mutations
156 P 19 0 19 0.003 0.426 View mutations
157 V 19 0 19 0.050 0.244 View mutations
158 K 19 0 19 0.075 0.381 View mutations
159 A 18 1 19 0.083 0.368 View mutations
160 G 4 15 19 0.715 0.705 View mutations
161 V 6 13 19 0.700 0.648 View mutations
162 E 2 17 19 0.898 0.672 View mutations
163 T 11 8 19 0.371 0.457 View mutations
164 T 15 4 19 0.280 0.343 View mutations
165 K 19 0 19 0.027 0.352 View mutations
166 P 13 6 19 0.405 0.377 View mutations
167 S 19 0 19 0.001 0.304 View mutations
168 K 18 1 19 0.076 0.279 View mutations
169 Q 19 0 19 0.005 0.325 View mutations
170 S 19 0 19 0.003 0.341 View mutations
171 N 19 0 19 0.040 0.286 View mutations
172 N 19 0 19 0.010 0.304 View mutations
173 K 19 0 19 0.024 0.273 View mutations
174 Y 19 0 19 0.006 0.082 View mutations
175 A 19 0 19 0.041 0.372 View mutations