B9A064 (IGLL5)

Overview
Predicted structure (AF):
AF-B9A064-F1-model_v4
Uniprot entry:
B9A064
Gene:
IGLL5
Protein length:
214 residues
Mutations found:
4065
Benign based on D2Deep prediction:
3327 out of 4065 mutations
Pathogenic based on D2Deep prediction:
738 out of 4065 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4065 mutations across 214 unique positions. There are 3327 benign and 738 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 A 17 2 19 0.139 0.227 View mutations
177 S 15 4 19 0.226 0.307 View mutations
178 S 18 1 19 0.152 0.053 View mutations
179 Y 17 2 19 0.152 0.283 View mutations
180 L 19 0 19 0.016 0.060 View mutations
181 S 18 1 19 0.051 0.402 View mutations
182 L 17 2 19 0.210 0.374 View mutations
183 T 19 0 19 0.012 0.404 View mutations
184 P 19 0 19 0.087 0.441 View mutations
185 E 19 0 19 0.001 0.425 View mutations
186 Q 19 0 19 0.033 0.409 View mutations
187 W 15 4 19 0.277 0.438 View mutations
188 K 19 0 19 0.017 0.500 View mutations
189 S 16 3 19 0.234 0.423 View mutations
190 H 19 0 19 0.036 0.557 View mutations
191 R 18 1 19 0.077 0.465 View mutations
192 S 18 1 19 0.074 0.459 View mutations
193 Y 10 9 19 0.509 0.492 View mutations
194 S 12 7 19 0.304 0.473 View mutations
195 C 8 11 19 0.610 0.553 View mutations
196 Q 18 1 19 0.078 0.402 View mutations
197 V 19 0 19 0.015 0.106 View mutations
198 T 6 13 19 0.700 0.574 View mutations
199 H 19 0 19 0.042 0.194 View mutations
200 E 11 8 19 0.465 0.467 View mutations