O14521 (SDHD)

Overview
Predicted structure (AF):
AF-O14521-F1-model_v4
Uniprot entry:
O14521
Gene:
SDHD
Protein length:
159 residues
Mutations found:
3020
Benign based on D2Deep prediction:
1994 out of 3020 mutations
Pathogenic based on D2Deep prediction:
1026 out of 3020 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3020 mutations across 159 unique positions. There are 1994 benign and 1026 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 11 7 18 0.355 0.496 View mutations
2 A 19 0 19 0.033 0.742 View mutations
3 V 16 3 19 0.164 0.715 View mutations
4 L 19 0 19 0.039 0.793 View mutations
5 W 19 0 19 0.001 0.871 View mutations
6 R 19 0 19 0.009 0.781 View mutations
7 L 19 0 19 0.007 0.842 View mutations
8 S 19 0 19 0.003 0.847 View mutations
9 A 19 0 19 0.003 0.870 View mutations
10 V 19 0 19 0.005 0.846 View mutations
11 C 19 0 19 0.001 0.908 View mutations
12 G 19 0 19 0.091 0.927 View mutations
13 A 19 0 19 0.003 0.938 View mutations
14 L 19 0 19 0.021 0.928 View mutations
15 G 19 0 19 0.002 0.921 View mutations
16 G 19 0 19 0.001 0.938 View mutations
17 R 19 0 19 0.040 0.933 View mutations
18 A 18 1 19 0.029 0.851 View mutations
19 L 19 0 19 0.001 0.896 View mutations
20 L 19 0 19 0.001 0.900 View mutations
21 L 18 1 19 0.074 0.885 View mutations
22 R 19 0 19 0.000 0.893 View mutations
23 T 18 1 19 0.077 0.795 View mutations
24 P 18 1 19 0.065 0.841 View mutations
25 V 15 4 19 0.193 0.688 View mutations