O14521 (SDHD)

Overview
Predicted structure (AF):
AF-O14521-F1-model_v4
Uniprot entry:
O14521
Gene:
SDHD
Protein length:
159 residues
Mutations found:
3020
Benign based on D2Deep prediction:
1994 out of 3020 mutations
Pathogenic based on D2Deep prediction:
1026 out of 3020 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3020 mutations across 159 unique positions. There are 1994 benign and 1026 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 V 19 0 19 0.001 0.861 View mutations
27 R 19 0 19 0.018 0.902 View mutations
28 P 19 0 19 0.074 0.751 View mutations
29 A 19 0 19 0.034 0.826 View mutations
30 H 19 0 19 0.002 0.883 View mutations
31 I 19 0 19 0.000 0.846 View mutations
32 S 19 0 19 0.000 0.884 View mutations
33 A 18 1 19 0.038 0.856 View mutations
34 F 19 0 19 0.001 0.927 View mutations
35 L 19 0 19 0.000 0.916 View mutations
36 Q 19 0 19 0.000 0.925 View mutations
37 D 19 0 19 0.012 0.829 View mutations
38 R 19 0 19 0.008 0.950 View mutations
39 P 19 0 19 0.004 0.962 View mutations
40 I 19 0 19 0.001 0.996 View mutations
41 P 17 2 19 0.185 0.856 View mutations
42 E 19 0 19 0.001 1.000 View mutations
43 W 19 0 19 0.000 0.976 View mutations
44 C 19 0 19 0.000 0.983 View mutations
45 G 18 1 19 0.049 0.851 View mutations
46 V 19 0 19 0.007 0.884 View mutations
47 Q 14 5 19 0.258 0.683 View mutations
48 H 19 0 19 0.016 0.872 View mutations
49 I 14 5 19 0.341 0.652 View mutations
50 H 16 3 19 0.250 0.702 View mutations