O14521 (SDHD)

Overview
Predicted structure (AF):
AF-O14521-F1-model_v4
Uniprot entry:
O14521
Gene:
SDHD
Protein length:
159 residues
Mutations found:
3020
Benign based on D2Deep prediction:
1994 out of 3020 mutations
Pathogenic based on D2Deep prediction:
1026 out of 3020 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3020 mutations across 159 unique positions. There are 1994 benign and 1026 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 K 13 6 19 0.378 0.444 View mutations
152 A 1 18 19 0.955 0.815 View mutations
153 V 11 8 19 0.472 0.442 View mutations
154 A 18 1 19 0.055 0.300 View mutations
155 M 2 17 19 0.914 0.663 View mutations
156 L 11 8 19 0.443 0.444 View mutations
157 W 14 5 19 0.348 0.378 View mutations
158 K 10 9 19 0.480 0.496 View mutations
159 L 19 0 19 0.034 0.336 View mutations