O14521 (SDHD)

Overview
Predicted structure (AF):
AF-O14521-F1-model_v4
Uniprot entry:
O14521
Gene:
SDHD
Protein length:
159 residues
Mutations found:
3020
Benign based on D2Deep prediction:
1994 out of 3020 mutations
Pathogenic based on D2Deep prediction:
1026 out of 3020 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3020 mutations across 159 unique positions. There are 1994 benign and 1026 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 L 19 0 19 0.008 0.347 View mutations
102 H 18 1 19 0.078 0.346 View mutations
103 G 3 16 19 0.811 0.666 View mutations
104 H 1 18 19 0.918 0.625 View mutations
105 W 0 19 19 1.000 0.724 View mutations
106 G 1 18 19 0.940 0.798 View mutations
107 L 11 8 19 0.418 0.465 View mutations
108 G 7 12 19 0.711 0.540 View mutations
109 Q 17 2 19 0.123 0.319 View mutations
110 V 19 0 19 0.036 0.237 View mutations
111 V 10 9 19 0.499 0.492 View mutations
112 T 6 13 19 0.596 0.583 View mutations
113 D 18 1 19 0.061 0.231 View mutations
114 Y 19 0 19 0.015 0.248 View mutations
115 V 7 12 19 0.703 0.534 View mutations
116 H 18 1 19 0.183 0.490 View mutations
117 G 8 11 19 0.526 0.435 View mutations
118 D 19 0 19 0.005 0.373 View mutations
119 A 18 1 19 0.047 0.556 View mutations
120 L 19 0 19 0.001 0.520 View mutations
121 Q 15 4 19 0.287 0.487 View mutations
122 K 19 0 19 0.013 0.441 View mutations
123 A 13 6 19 0.343 0.437 View mutations
124 A 11 8 19 0.473 0.487 View mutations
125 K 10 9 19 0.472 0.495 View mutations