O14521 (SDHD)

Overview
Predicted structure (AF):
AF-O14521-F1-model_v4
Uniprot entry:
O14521
Gene:
SDHD
Protein length:
159 residues
Mutations found:
3020
Benign based on D2Deep prediction:
1994 out of 3020 mutations
Pathogenic based on D2Deep prediction:
1026 out of 3020 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3020 mutations across 159 unique positions. There are 1994 benign and 1026 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 A 12 7 19 0.374 0.422 View mutations
127 G 2 17 19 0.864 0.522 View mutations
128 L 3 16 19 0.886 0.623 View mutations
129 L 14 5 19 0.260 0.463 View mutations
130 A 8 11 19 0.555 0.436 View mutations
131 L 3 16 19 0.828 0.633 View mutations
132 S 0 19 19 0.976 0.743 View mutations
133 A 10 9 19 0.490 0.498 View mutations
134 L 6 13 19 0.696 0.536 View mutations
135 T 6 13 19 0.674 0.623 View mutations
136 F 0 19 19 0.969 0.782 View mutations
137 A 3 16 19 0.861 0.592 View mutations
138 G 0 19 19 0.978 0.805 View mutations
139 L 1 18 19 0.876 0.947 View mutations
140 C 1 18 19 0.886 0.749 View mutations
141 Y 4 15 19 0.794 0.616 View mutations
142 F 19 0 19 0.022 0.127 View mutations
143 N 19 0 19 0.000 0.163 View mutations
144 Y 10 9 19 0.499 0.487 View mutations
145 H 19 0 19 0.011 0.393 View mutations
146 D 19 0 19 0.004 0.149 View mutations
147 V 6 13 19 0.703 0.631 View mutations
148 G 19 0 19 0.002 0.119 View mutations
149 I 12 7 19 0.373 0.397 View mutations
150 C 19 0 19 0.000 0.319 View mutations