O14757 (CHEK1)
Overview
- Predicted structure (AF):
- AF-O14757-F1-model_v4
- Uniprot entry:
- O14757
- Gene:
- CHEK1
- Protein length:
- 476 residues
- Mutations found:
- 9043
- Benign based on D2Deep prediction:
- 5640 out of 9043 mutations
- Pathogenic based on D2Deep prediction:
- 3403 out of 9043 mutations
- Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Long range effect of the mutations
Short range effect of the mutations
Positions
Download displayed results as CSVTable results: 9043 mutations across 476 unique positions. There are 5640 benign and 3403 pathogenic mutations.
| Position | Original | Benign | Pathogenic | Total | D2Deep score mean | Overall confidence mean | Actions |
|---|---|---|---|---|---|---|---|
| 476 | T | 19 | 0 | 19 | 0.002 | 0.574 | View mutations |