O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 17 1 18 0.076 0.503 View mutations
2 A 13 6 19 0.373 0.518 View mutations
3 Y 7 12 19 0.664 0.415 View mutations
4 H 14 5 19 0.281 0.528 View mutations
5 S 19 0 19 0.047 0.531 View mutations
6 F 19 0 19 0.014 0.511 View mutations
7 L 18 1 19 0.038 0.547 View mutations
8 V 19 0 19 0.002 0.521 View mutations
9 E 15 4 19 0.248 0.478 View mutations
10 P 12 7 19 0.347 0.494 View mutations
11 I 19 0 19 0.024 0.439 View mutations
12 S 10 9 19 0.469 0.421 View mutations
13 C 14 5 19 0.327 0.413 View mutations
14 H 4 15 19 0.716 0.423 View mutations
15 A 19 0 19 0.003 0.472 View mutations
16 W 17 2 19 0.117 0.441 View mutations
17 N 4 15 19 0.760 0.505 View mutations
18 K 16 3 19 0.212 0.457 View mutations
19 D 4 15 19 0.724 0.398 View mutations
20 R 18 1 19 0.050 0.490 View mutations
21 T 2 17 19 0.853 0.430 View mutations
22 Q 17 2 19 0.107 0.466 View mutations
23 I 6 13 19 0.677 0.430 View mutations
24 A 1 18 19 0.941 0.506 View mutations
25 I 7 12 19 0.670 0.438 View mutations