O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 H 0 19 19 0.976 0.502 View mutations
52 N 5 14 19 0.729 0.523 View mutations
53 G 0 19 19 1.000 0.478 View mutations
54 Q 8 11 19 0.520 0.435 View mutations
55 V 14 5 19 0.263 0.476 View mutations
56 T 7 12 19 0.634 0.537 View mutations
57 G 0 19 19 0.969 0.555 View mutations
58 I 18 1 19 0.062 0.434 View mutations
59 D 4 15 19 0.791 0.525 View mutations
60 W 4 15 19 0.782 0.526 View mutations
61 A 2 17 19 0.813 0.483 View mutations
62 P 2 17 19 0.871 0.533 View mutations
63 E 19 0 19 0.056 0.577 View mutations
64 S 17 2 19 0.135 0.429 View mutations
65 N 15 4 19 0.227 0.423 View mutations
66 R 12 7 19 0.396 0.422 View mutations
67 I 7 12 19 0.600 0.436 View mutations
68 V 1 18 19 0.929 0.520 View mutations
69 T 12 7 19 0.356 0.495 View mutations
70 C 5 14 19 0.623 0.458 View mutations
71 G 2 17 19 0.898 0.408 View mutations
72 T 7 12 19 0.636 0.504 View mutations
73 D 0 19 19 1.000 0.566 View mutations
74 R 0 19 19 0.974 0.615 View mutations
75 N 5 14 19 0.760 0.578 View mutations