O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 C 18 1 19 0.072 0.420 View mutations
27 P 9 10 19 0.448 0.437 View mutations
28 N 10 9 19 0.466 0.496 View mutations
29 N 12 7 19 0.420 0.444 View mutations
30 H 8 11 19 0.569 0.434 View mutations
31 E 18 1 19 0.118 0.475 View mutations
32 V 10 9 19 0.527 0.495 View mutations
33 H 14 5 19 0.233 0.441 View mutations
34 I 18 1 19 0.121 0.380 View mutations
35 Y 4 15 19 0.728 0.518 View mutations
36 E 19 0 19 0.008 0.561 View mutations
37 K 18 1 19 0.115 0.431 View mutations
38 S 12 7 19 0.386 0.537 View mutations
39 G 8 11 19 0.565 0.435 View mutations
40 A 18 1 19 0.067 0.630 View mutations
41 K 13 6 19 0.343 0.459 View mutations
42 W 14 5 19 0.309 0.429 View mutations
43 T 19 0 19 0.000 0.533 View mutations
44 K 19 0 19 0.071 0.461 View mutations
45 V 7 12 19 0.572 0.414 View mutations
46 H 13 6 19 0.331 0.477 View mutations
47 E 18 1 19 0.071 0.446 View mutations
48 L 9 10 19 0.495 0.507 View mutations
49 K 9 10 19 0.595 0.433 View mutations
50 E 0 19 19 1.000 0.558 View mutations