O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 D 4 15 19 0.722 0.460 View mutations
352 G 2 17 19 0.861 0.597 View mutations
353 G 6 13 19 0.712 0.417 View mutations
354 M 13 6 19 0.330 0.441 View mutations
355 S 11 8 19 0.436 0.443 View mutations
356 I 19 0 19 0.008 0.398 View mutations
357 W 12 7 19 0.335 0.499 View mutations
358 D 15 4 19 0.208 0.491 View mutations
359 V 10 9 19 0.432 0.438 View mutations
360 K 18 1 19 0.056 0.573 View mutations
361 S 19 0 19 0.003 0.579 View mutations
362 L 6 13 19 0.685 0.405 View mutations
363 E 1 18 19 0.937 0.315 View mutations
364 S 9 10 19 0.562 0.451 View mutations
365 A 18 1 19 0.081 0.549 View mutations
366 L 10 9 19 0.447 0.470 View mutations
367 K 12 7 19 0.377 0.499 View mutations
368 D 5 14 19 0.742 0.414 View mutations
369 L 17 2 19 0.080 0.524 View mutations
370 K 16 3 19 0.164 0.529 View mutations
371 I 15 4 19 0.205 0.475 View mutations
372 K 19 0 19 0.004 0.629 View mutations