O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 K 19 0 19 0.016 0.431 View mutations
327 N 14 5 19 0.241 0.424 View mutations
328 S 15 4 19 0.219 0.440 View mutations
329 V 13 6 19 0.328 0.422 View mutations
330 S 13 6 19 0.266 0.476 View mutations
331 Q 11 8 19 0.523 0.482 View mutations
332 I 5 14 19 0.684 0.377 View mutations
333 S 19 0 19 0.020 0.747 View mutations
334 V 18 1 19 0.059 0.663 View mutations
335 L 19 0 19 0.001 0.744 View mutations
336 S 19 0 19 0.001 0.710 View mutations
337 G 19 0 19 0.000 0.710 View mutations
338 G 19 0 19 0.006 0.768 View mutations
339 K 19 0 19 0.000 0.749 View mutations
340 A 13 6 19 0.280 0.581 View mutations
341 K 19 0 19 0.000 0.792 View mutations
342 C 17 2 19 0.073 0.647 View mutations
343 S 18 1 19 0.059 0.666 View mutations
344 Q 8 11 19 0.592 0.432 View mutations
345 F 18 1 19 0.047 0.540 View mutations
346 C 19 0 19 0.015 0.531 View mutations
347 T 8 11 19 0.574 0.436 View mutations
348 T 12 7 19 0.397 0.432 View mutations
349 G 7 12 19 0.687 0.501 View mutations
350 M 19 0 19 0.025 0.445 View mutations