O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 R 19 0 19 0.002 0.468 View mutations
302 F 19 0 19 0.003 0.474 View mutations
303 Q 5 14 19 0.738 0.413 View mutations
304 N 7 12 19 0.662 0.433 View mutations
305 L 19 0 19 0.003 0.429 View mutations
306 D 19 0 19 0.001 0.365 View mutations
307 K 19 0 19 0.000 0.483 View mutations
308 K 19 0 19 0.000 0.549 View mutations
309 A 19 0 19 0.023 0.479 View mutations
310 S 18 1 19 0.063 0.751 View mutations
311 S 19 0 19 0.005 0.788 View mutations
312 E 19 0 19 0.000 0.777 View mutations
313 G 19 0 19 0.000 0.927 View mutations
314 G 19 0 19 0.001 0.987 View mutations
315 T 19 0 19 0.001 1.000 View mutations
316 A 19 0 19 0.001 0.955 View mutations
317 A 19 0 19 0.000 0.986 View mutations
318 G 19 0 19 0.000 0.973 View mutations
319 A 19 0 19 0.002 0.943 View mutations
320 G 19 0 19 0.008 0.911 View mutations
321 L 19 0 19 0.028 0.679 View mutations
322 D 19 0 19 0.000 0.685 View mutations
323 S 19 0 19 0.000 0.569 View mutations
324 L 13 6 19 0.324 0.510 View mutations
325 H 0 19 19 0.999 0.428 View mutations