O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
851 E 9 10 19 0.537 0.518 View mutations
852 E 7 12 19 0.688 0.605 View mutations
853 K 0 19 19 0.957 0.818 View mutations
854 I 0 19 19 0.974 0.818 View mutations
855 I 1 18 19 0.958 0.797 View mutations
856 G 0 19 19 0.987 0.848 View mutations
857 K 7 12 19 0.611 0.583 View mutations
858 V 6 13 19 0.662 0.631 View mutations
859 E 7 12 19 0.577 0.581 View mutations
860 K 10 9 19 0.493 0.487 View mutations
861 V 19 0 19 0.003 0.246 View mutations
862 D 19 0 19 0.079 0.233 View mutations