O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 10 8 18 0.453 0.441 View mutations
2 N 15 4 19 0.231 0.578 View mutations
3 I 4 15 19 0.740 0.339 View mutations
4 Q 16 3 19 0.164 0.700 View mutations
5 E 17 2 19 0.115 0.654 View mutations
6 Q 19 0 19 0.002 0.813 View mutations
7 G 19 0 19 0.000 0.695 View mutations
8 F 19 0 19 0.004 0.731 View mutations
9 P 14 5 19 0.235 0.572 View mutations
10 L 19 0 19 0.069 0.681 View mutations
11 D 18 1 19 0.066 0.508 View mutations
12 L 11 8 19 0.506 0.469 View mutations
13 G 12 7 19 0.421 0.466 View mutations
14 A 7 12 19 0.638 0.426 View mutations
15 S 19 0 19 0.052 0.442 View mutations
16 F 19 0 19 0.011 0.485 View mutations
17 T 10 9 19 0.414 0.432 View mutations
18 E 0 19 19 0.989 0.533 View mutations
19 D 0 19 19 0.974 0.589 View mutations
20 A 12 7 19 0.389 0.480 View mutations
21 P 0 19 19 1.000 0.596 View mutations
22 R 2 17 19 0.875 0.526 View mutations
23 P 0 19 19 1.000 0.679 View mutations
24 P 0 19 19 1.000 0.709 View mutations
25 V 0 19 19 0.997 0.758 View mutations