O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
826 K 19 0 19 0.007 0.211 View mutations
827 V 19 0 19 0.001 0.174 View mutations
828 S 19 0 19 0.000 0.220 View mutations
829 D 19 0 19 0.000 0.244 View mutations
830 E 18 1 19 0.113 0.249 View mutations
831 F 3 16 19 0.766 0.707 View mutations
832 D 18 1 19 0.094 0.189 View mutations
833 C 15 4 19 0.232 0.341 View mutations
834 G 17 2 19 0.100 0.192 View mutations
835 V 18 1 19 0.052 0.160 View mutations
836 V 19 0 19 0.013 0.067 View mutations
837 F 16 3 19 0.153 0.230 View mutations
838 E 4 15 19 0.731 0.742 View mutations
839 E 0 19 19 0.970 0.877 View mutations
840 V 0 19 19 0.996 0.836 View mutations
841 R 0 19 19 0.990 0.661 View mutations
842 E 1 18 19 0.958 0.648 View mutations
843 D 0 19 19 0.999 0.695 View mutations
844 E 9 10 19 0.486 0.504 View mutations
845 A 0 19 19 0.998 0.640 View mutations
846 V 1 18 19 0.947 0.566 View mutations
847 L 0 19 19 1.000 0.836 View mutations
848 P 0 19 19 1.000 0.800 View mutations
849 V 2 17 19 0.902 0.717 View mutations
850 F 1 18 19 0.933 0.779 View mutations