O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
801 R 3 16 19 0.880 0.521 View mutations
802 G 5 14 19 0.661 0.579 View mutations
803 R 5 14 19 0.726 0.562 View mutations
804 A 5 14 19 0.748 0.530 View mutations
805 V 12 7 19 0.389 0.440 View mutations
806 T 4 15 19 0.727 0.606 View mutations
807 L 0 19 19 1.000 0.787 View mutations
808 G 0 19 19 1.000 0.761 View mutations
809 Q 8 11 19 0.541 0.551 View mutations
810 F 19 0 19 0.035 0.215 View mutations
811 K 0 19 19 0.988 0.803 View mutations
812 E 3 16 19 0.761 0.747 View mutations
813 L 19 0 19 0.009 0.053 View mutations
814 L 19 0 19 0.008 0.095 View mutations
815 T 5 14 19 0.764 0.675 View mutations
816 K 18 1 19 0.135 0.241 View mutations
817 K 19 0 19 0.001 0.216 View mutations
818 G 19 0 19 0.013 0.198 View mutations
819 S 14 5 19 0.231 0.447 View mutations
820 Y 19 0 19 0.001 0.212 View mutations
821 R 16 3 19 0.190 0.272 View mutations
822 Y 19 0 19 0.000 0.240 View mutations
823 Y 19 0 19 0.000 0.259 View mutations
824 F 19 0 19 0.000 0.134 View mutations
825 K 19 0 19 0.000 0.137 View mutations