O15315-3 (RAD51B)

Overview
Predicted structure (AF):
AF-O15315-3-F1-model_v4
Uniprot entry:
O15315-3
Gene:
RAD51B
Protein length:
384 residues
Mutations found:
7295
Benign based on D2Deep prediction:
3777 out of 7295 mutations
Pathogenic based on D2Deep prediction:
3518 out of 7295 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7295 mutations across 384 unique positions. There are 3777 benign and 3518 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 S 18 1 19 0.056 0.935 View mutations
352 V 14 5 19 0.269 0.732 View mutations
353 T 18 1 19 0.050 0.907 View mutations
354 Q 15 4 19 0.195 0.753 View mutations
355 A 18 1 19 0.036 0.841 View mutations
356 E 11 8 19 0.446 0.549 View mutations
357 L 13 6 19 0.275 0.640 View mutations
358 N 11 8 19 0.497 0.547 View mutations
359 W 11 8 19 0.399 0.550 View mutations
360 A 19 0 19 0.007 0.904 View mutations
361 P 7 12 19 0.625 0.389 View mutations
362 E 16 3 19 0.136 0.721 View mutations
363 I 18 1 19 0.102 0.777 View mutations
364 L 19 0 19 0.047 0.757 View mutations
365 P 15 4 19 0.255 0.636 View mutations
366 P 16 3 19 0.124 0.685 View mutations
367 Q 11 8 19 0.375 0.525 View mutations
368 P 18 1 19 0.051 0.680 View mutations
369 P 14 5 19 0.281 0.567 View mutations
370 E 15 4 19 0.228 0.619 View mutations
371 Q 15 4 19 0.235 0.566 View mutations
372 L 11 8 19 0.472 0.491 View mutations
373 G 15 4 19 0.224 0.543 View mutations
374 L 14 5 19 0.301 0.528 View mutations
375 Q 11 8 19 0.417 0.473 View mutations