O15315-3 (RAD51B)

Overview
Predicted structure (AF):
AF-O15315-3-F1-model_v4
Uniprot entry:
O15315-3
Gene:
RAD51B
Protein length:
384 residues
Mutations found:
7295
Benign based on D2Deep prediction:
3777 out of 7295 mutations
Pathogenic based on D2Deep prediction:
3518 out of 7295 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7295 mutations across 384 unique positions. There are 3777 benign and 3518 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 P 5 14 19 0.706 0.402 View mutations
327 L 13 6 19 0.312 0.539 View mutations
328 A 10 9 19 0.494 0.462 View mutations
329 P 15 4 19 0.197 0.579 View mutations
330 F 3 16 19 0.818 0.311 View mutations
331 T 4 15 19 0.794 0.298 View mutations
332 S 9 10 19 0.553 0.460 View mutations
333 F 13 6 19 0.355 0.589 View mutations
334 V 17 2 19 0.214 0.778 View mutations
335 Y 18 1 19 0.052 0.642 View mutations
336 T 19 0 19 0.000 0.799 View mutations
337 I 19 0 19 0.000 0.611 View mutations
338 K 18 1 19 0.075 0.755 View mutations
339 E 18 1 19 0.036 0.762 View mutations
340 E 13 6 19 0.357 0.547 View mutations
341 G 19 0 19 0.000 0.579 View mutations
342 L 16 3 19 0.187 0.578 View mutations
343 V 19 0 19 0.060 0.719 View mutations
344 L 9 10 19 0.477 0.458 View mutations
345 Q 19 0 19 0.000 0.834 View mutations
346 E 11 8 19 0.395 0.558 View mutations
347 T 19 0 19 0.001 0.939 View mutations
348 T 19 0 19 0.008 0.975 View mutations
349 F 16 3 19 0.128 0.807 View mutations
350 C 7 12 19 0.673 0.368 View mutations