O15315-3 (RAD51B)

Overview
Predicted structure (AF):
AF-O15315-3-F1-model_v4
Uniprot entry:
O15315-3
Gene:
RAD51B
Protein length:
384 residues
Mutations found:
7295
Benign based on D2Deep prediction:
3777 out of 7295 mutations
Pathogenic based on D2Deep prediction:
3518 out of 7295 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 7295 mutations across 384 unique positions. There are 3777 benign and 3518 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 S 18 1 19 0.066 0.380 View mutations
302 H 19 0 19 0.016 0.406 View mutations
303 S 4 15 19 0.772 0.407 View mutations
304 V 0 19 19 0.999 0.449 View mutations
305 N 19 0 19 0.000 0.467 View mutations
306 T 14 5 19 0.238 0.419 View mutations
307 R 18 1 19 0.177 0.436 View mutations
308 L 9 10 19 0.532 0.444 View mutations
309 I 19 0 19 0.020 0.589 View mutations
310 L 9 10 19 0.472 0.450 View mutations
311 Q 18 1 19 0.038 0.594 View mutations
312 Y 19 0 19 0.000 0.764 View mutations
313 L 19 0 19 0.000 0.837 View mutations
314 D 19 0 19 0.016 0.864 View mutations
315 S 19 0 19 0.061 0.818 View mutations
316 E 18 1 19 0.086 0.797 View mutations
317 R 19 0 19 0.001 0.918 View mutations
318 R 19 0 19 0.000 0.698 View mutations
319 Q 17 2 19 0.140 0.690 View mutations
320 I 13 6 19 0.291 0.591 View mutations
321 L 16 3 19 0.166 0.701 View mutations
322 I 7 12 19 0.538 0.395 View mutations
323 A 19 0 19 0.000 0.659 View mutations
324 K 1 18 19 0.910 0.300 View mutations
325 S 1 18 19 0.926 0.305 View mutations