O15315-3 (RAD51B)

Overview
Predicted structure (AF):
AF-O15315-3-F1-model_v4
Uniprot entry:
O15315-3
Gene:
RAD51B
Protein length:
384 residues
Mutations found:
7295
Benign based on D2Deep prediction:
3777 out of 7295 mutations
Pathogenic based on D2Deep prediction:
3518 out of 7295 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7295 mutations across 384 unique positions. There are 3777 benign and 3518 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 K 18 1 19 0.143 0.508 View mutations
177 V 1 18 19 0.898 0.567 View mutations
178 H 13 6 19 0.349 0.427 View mutations
179 L 3 16 19 0.838 0.561 View mutations
180 Y 6 13 19 0.690 0.447 View mutations
181 R 12 7 19 0.382 0.472 View mutations
182 E 1 18 19 0.956 0.593 View mutations
183 L 8 11 19 0.574 0.510 View mutations
184 T 4 15 19 0.738 0.460 View mutations
185 C 15 4 19 0.279 0.465 View mutations
186 D 19 0 19 0.014 0.578 View mutations
187 E 9 10 19 0.558 0.437 View mutations
188 V 19 0 19 0.080 0.431 View mutations
189 L 2 17 19 0.893 0.503 View mutations
190 Q 15 4 19 0.214 0.531 View mutations
191 R 1 18 19 0.921 0.583 View mutations
192 I 4 15 19 0.802 0.526 View mutations
193 E 18 1 19 0.137 0.508 View mutations
194 S 2 17 19 0.889 0.460 View mutations
195 L 7 12 19 0.620 0.528 View mutations
196 E 4 15 19 0.804 0.570 View mutations
197 E 15 4 19 0.172 0.432 View mutations
198 E 3 16 19 0.833 0.507 View mutations
199 I 1 18 19 0.945 0.573 View mutations
200 I 1 18 19 0.962 0.592 View mutations