O15315-3 (RAD51B)

Overview
Predicted structure (AF):
AF-O15315-3-F1-model_v4
Uniprot entry:
O15315-3
Gene:
RAD51B
Protein length:
384 residues
Mutations found:
7295
Benign based on D2Deep prediction:
3777 out of 7295 mutations
Pathogenic based on D2Deep prediction:
3518 out of 7295 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7295 mutations across 384 unique positions. There are 3777 benign and 3518 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 S 6 13 19 0.663 0.530 View mutations
202 K 19 0 19 0.024 0.443 View mutations
203 G 19 0 19 0.001 0.415 View mutations
204 I 19 0 19 0.000 0.359 View mutations
205 K 1 18 19 0.945 0.597 View mutations
206 L 0 19 19 0.993 0.636 View mutations
207 V 2 17 19 0.906 0.591 View mutations
208 I 3 16 19 0.840 0.657 View mutations
209 L 10 9 19 0.479 0.491 View mutations
210 D 5 14 19 0.726 0.663 View mutations
211 S 3 16 19 0.798 0.784 View mutations
212 V 1 18 19 0.907 0.772 View mutations
213 A 2 17 19 0.893 0.789 View mutations
214 S 2 17 19 0.859 0.895 View mutations
215 V 2 17 19 0.882 0.800 View mutations
216 V 1 18 19 0.959 0.798 View mutations
217 R 2 17 19 0.852 0.855 View mutations
218 K 16 3 19 0.281 0.282 View mutations
219 E 18 1 19 0.075 0.200 View mutations
220 F 19 0 19 0.003 0.203 View mutations
221 D 19 0 19 0.000 0.336 View mutations
222 A 17 2 19 0.120 0.425 View mutations
223 Q 19 0 19 0.000 0.368 View mutations
224 L 15 4 19 0.225 0.453 View mutations
225 Q 19 0 19 0.022 0.487 View mutations