O15315-3 (RAD51B)

Overview
Predicted structure (AF):
AF-O15315-3-F1-model_v4
Uniprot entry:
O15315-3
Gene:
RAD51B
Protein length:
384 residues
Mutations found:
7295
Benign based on D2Deep prediction:
3777 out of 7295 mutations
Pathogenic based on D2Deep prediction:
3518 out of 7295 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7295 mutations across 384 unique positions. There are 3777 benign and 3518 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 G 8 11 19 0.503 0.518 View mutations
227 N 18 1 19 0.048 0.450 View mutations
228 L 5 14 19 0.704 0.531 View mutations
229 K 2 17 19 0.907 0.399 View mutations
230 E 2 17 19 0.891 0.514 View mutations
231 R 1 18 19 0.934 0.662 View mutations
232 N 2 17 19 0.894 0.585 View mutations
233 K 1 18 19 0.964 0.464 View mutations
234 F 1 18 19 0.939 0.447 View mutations
235 L 4 15 19 0.809 0.599 View mutations
236 A 17 2 19 0.156 0.497 View mutations
237 R 4 15 19 0.797 0.425 View mutations
238 E 0 19 19 0.976 0.515 View mutations
239 A 1 18 19 0.961 0.611 View mutations
240 S 14 5 19 0.242 0.487 View mutations
241 S 16 3 19 0.216 0.465 View mutations
242 L 0 19 19 0.996 0.709 View mutations
243 K 1 18 19 0.936 0.627 View mutations
244 Y 18 1 19 0.056 0.475 View mutations
245 L 0 19 19 0.979 0.642 View mutations
246 A 1 18 19 0.938 0.672 View mutations
247 E 18 1 19 0.058 0.388 View mutations
248 E 4 15 19 0.782 0.564 View mutations
249 F 0 19 19 1.000 0.703 View mutations
250 S 5 14 19 0.771 0.546 View mutations