O15524 (O15524)

Overview
Predicted structure (AF):
AF-O15524-F1-model_v4
Uniprot entry:
O15524
Gene:
O15524
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
3142 out of 4008 mutations
Pathogenic based on D2Deep prediction:
866 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4008 mutations across 211 unique positions. There are 3142 benign and 866 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 16 2 18 0.166 0.474 View mutations
2 V 15 4 19 0.258 0.493 View mutations
3 A 15 4 19 0.213 0.432 View mutations
4 H 18 1 19 0.087 0.546 View mutations
5 N 19 0 19 0.027 0.562 View mutations
6 Q 18 1 19 0.107 0.624 View mutations
7 V 19 0 19 0.000 0.495 View mutations
8 A 19 0 19 0.044 0.619 View mutations
9 A 19 0 19 0.010 0.672 View mutations
10 D 18 1 19 0.079 0.550 View mutations
11 N 19 0 19 0.002 0.697 View mutations
12 A 19 0 19 0.006 0.688 View mutations
13 V 19 0 19 0.039 0.692 View mutations
14 S 19 0 19 0.010 0.831 View mutations
15 T 19 0 19 0.004 0.884 View mutations
16 A 19 0 19 0.002 0.867 View mutations
17 A 19 0 19 0.002 0.824 View mutations
18 E 17 2 19 0.144 0.748 View mutations
19 P 18 1 19 0.079 0.812 View mutations
20 R 19 0 19 0.019 0.895 View mutations
21 R 17 2 19 0.104 0.791 View mutations
22 R 19 0 19 0.005 0.857 View mutations
23 P 19 0 19 0.012 0.864 View mutations
24 E 10 9 19 0.471 0.507 View mutations
25 P 19 0 19 0.002 0.978 View mutations