O15524 (O15524)

Overview
Predicted structure (AF):
AF-O15524-F1-model_v4
Uniprot entry:
O15524
Gene:
O15524
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
3142 out of 4008 mutations
Pathogenic based on D2Deep prediction:
866 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4008 mutations across 211 unique positions. There are 3142 benign and 866 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 S 19 0 19 0.004 0.989 View mutations
27 S 19 0 19 0.001 0.943 View mutations
28 S 19 0 19 0.006 1.000 View mutations
29 S 19 0 19 0.003 0.964 View mutations
30 S 19 0 19 0.003 0.957 View mutations
31 S 19 0 19 0.000 0.944 View mutations
32 S 19 0 19 0.001 0.923 View mutations
33 P 19 0 19 0.010 0.925 View mutations
34 A 19 0 19 0.000 0.887 View mutations
35 A 18 1 19 0.048 0.855 View mutations
36 P 19 0 19 0.002 0.894 View mutations
37 A 19 0 19 0.001 0.923 View mutations
38 R 19 0 19 0.010 0.918 View mutations
39 P 19 0 19 0.042 0.918 View mutations
40 R 19 0 19 0.003 0.921 View mutations
41 P 19 0 19 0.003 0.911 View mutations
42 C 19 0 19 0.004 0.883 View mutations
43 P 19 0 19 0.004 0.901 View mutations
44 A 19 0 19 0.017 0.914 View mutations
45 V 18 1 19 0.098 0.848 View mutations
46 P 19 0 19 0.000 0.888 View mutations
47 A 19 0 19 0.000 0.828 View mutations
48 P 19 0 19 0.001 0.820 View mutations
49 A 19 0 19 0.009 0.823 View mutations
50 P 13 6 19 0.284 0.586 View mutations