O15524 (O15524)

Overview
Predicted structure (AF):
AF-O15524-F1-model_v4
Uniprot entry:
O15524
Gene:
O15524
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
3142 out of 4008 mutations
Pathogenic based on D2Deep prediction:
866 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4008 mutations across 211 unique positions. There are 3142 benign and 866 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 G 12 7 19 0.418 0.549 View mutations
52 D 18 1 19 0.094 0.562 View mutations
53 T 13 6 19 0.371 0.458 View mutations
54 H 19 0 19 0.035 0.373 View mutations
55 F 19 0 19 0.029 0.373 View mutations
56 R 19 0 19 0.003 0.473 View mutations
57 T 19 0 19 0.085 0.443 View mutations
58 F 18 1 19 0.133 0.452 View mutations
59 R 13 6 19 0.363 0.499 View mutations
60 S 5 14 19 0.689 0.446 View mutations
61 H 10 9 19 0.411 0.450 View mutations
62 A 7 12 19 0.621 0.427 View mutations
63 D 2 17 19 0.859 0.536 View mutations
64 Y 10 9 19 0.487 0.427 View mutations
65 R 19 0 19 0.082 0.599 View mutations
66 R 18 1 19 0.138 0.490 View mutations
67 I 4 15 19 0.789 0.553 View mutations
68 T 12 7 19 0.403 0.418 View mutations
69 R 14 5 19 0.325 0.471 View mutations
70 A 12 7 19 0.395 0.495 View mutations
71 S 3 16 19 0.823 0.466 View mutations
72 A 7 12 19 0.616 0.433 View mutations
73 L 4 15 19 0.737 0.519 View mutations
74 L 0 19 19 0.996 0.642 View mutations
75 D 1 18 19 0.936 0.559 View mutations