O15524 (O15524)

Overview
Predicted structure (AF):
AF-O15524-F1-model_v4
Uniprot entry:
O15524
Gene:
O15524
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
3142 out of 4008 mutations
Pathogenic based on D2Deep prediction:
866 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4008 mutations across 211 unique positions. There are 3142 benign and 866 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 A 10 9 19 0.523 0.425 View mutations
77 C 0 19 19 0.996 0.687 View mutations
78 G 0 19 19 1.000 0.771 View mutations
79 F 0 19 19 1.000 0.696 View mutations
80 Y 0 19 19 1.000 0.724 View mutations
81 W 0 19 19 0.992 0.695 View mutations
82 G 0 19 19 1.000 0.806 View mutations
83 P 0 19 19 0.991 0.745 View mutations
84 L 3 16 19 0.776 0.632 View mutations
85 S 16 3 19 0.258 0.487 View mutations
86 V 12 7 19 0.306 0.442 View mutations
87 H 19 0 19 0.011 0.375 View mutations
88 G 19 0 19 0.010 0.463 View mutations
89 A 10 9 19 0.508 0.485 View mutations
90 H 19 0 19 0.041 0.325 View mutations
91 E 19 0 19 0.003 0.449 View mutations
92 R 19 0 19 0.009 0.379 View mutations
93 L 19 0 19 0.056 0.354 View mutations
94 R 19 0 19 0.006 0.378 View mutations
95 A 18 1 19 0.077 0.392 View mutations
96 E 19 0 19 0.006 0.235 View mutations
97 P 19 0 19 0.002 0.294 View mutations
98 V 19 0 19 0.002 0.333 View mutations
99 G 19 0 19 0.001 0.195 View mutations
100 T 19 0 19 0.018 0.077 View mutations