O15524 (O15524)

Overview
Predicted structure (AF):
AF-O15524-F1-model_v4
Uniprot entry:
O15524
Gene:
O15524
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
3142 out of 4008 mutations
Pathogenic based on D2Deep prediction:
866 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4008 mutations across 211 unique positions. There are 3142 benign and 866 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 E 19 0 19 0.001 0.119 View mutations
177 L 19 0 19 0.014 0.123 View mutations
178 C 19 0 19 0.010 0.051 View mutations
179 R 19 0 19 0.000 0.133 View mutations
180 Q 19 0 19 0.003 0.422 View mutations
181 R 19 0 19 0.000 0.336 View mutations
182 I 19 0 19 0.002 0.221 View mutations
183 V 19 0 19 0.001 0.198 View mutations
184 A 19 0 19 0.002 0.461 View mutations
185 T 19 0 19 0.000 0.323 View mutations
186 V 19 0 19 0.000 0.396 View mutations
187 G 19 0 19 0.015 0.344 View mutations
188 R 13 6 19 0.327 0.491 View mutations
189 E 16 3 19 0.238 0.447 View mutations
190 N 17 2 19 0.188 0.448 View mutations
191 L 17 2 19 0.250 0.356 View mutations
192 A 19 0 19 0.003 0.424 View mutations
193 R 19 0 19 0.004 0.399 View mutations
194 I 16 3 19 0.254 0.400 View mutations
195 P 15 4 19 0.191 0.349 View mutations
196 L 13 6 19 0.375 0.408 View mutations
197 N 19 0 19 0.008 0.196 View mutations
198 P 19 0 19 0.034 0.265 View mutations
199 V 19 0 19 0.000 0.071 View mutations
200 L 18 1 19 0.102 0.116 View mutations