O15524 (O15524)

Overview
Predicted structure (AF):
AF-O15524-F1-model_v4
Uniprot entry:
O15524
Gene:
O15524
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
3142 out of 4008 mutations
Pathogenic based on D2Deep prediction:
866 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4008 mutations across 211 unique positions. There are 3142 benign and 866 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 I 1 18 19 0.846 0.776 View mutations
127 R 2 17 19 0.874 0.758 View mutations
128 V 5 14 19 0.694 0.659 View mutations
129 H 8 11 19 0.567 0.518 View mutations
130 F 7 12 19 0.598 0.576 View mutations
131 Q 6 13 19 0.708 0.530 View mutations
132 A 5 14 19 0.677 0.563 View mutations
133 G 7 12 19 0.686 0.581 View mutations
134 R 11 8 19 0.434 0.483 View mutations
135 F 1 18 19 0.781 0.845 View mutations
136 H 12 7 19 0.447 0.448 View mutations
137 L 12 7 19 0.415 0.388 View mutations
138 D 19 0 19 0.023 0.122 View mutations
139 G 9 10 19 0.468 0.523 View mutations
140 S 4 15 19 0.716 0.732 View mutations
141 R 14 5 19 0.258 0.410 View mutations
142 E 19 0 19 0.046 0.105 View mutations
143 S 18 1 19 0.054 0.316 View mutations
144 F 19 0 19 0.044 0.062 View mutations
145 D 19 0 19 0.011 0.285 View mutations
146 C 19 0 19 0.001 0.251 View mutations
147 L 19 0 19 0.007 0.128 View mutations
148 F 19 0 19 0.005 0.252 View mutations
149 E 19 0 19 0.000 0.324 View mutations
150 L 19 0 19 0.055 0.000 View mutations