O15524 (O15524)

Overview
Predicted structure (AF):
AF-O15524-F1-model_v4
Uniprot entry:
O15524
Gene:
O15524
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
3142 out of 4008 mutations
Pathogenic based on D2Deep prediction:
866 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4008 mutations across 211 unique positions. There are 3142 benign and 866 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 L 19 0 19 0.015 0.082 View mutations
152 E 19 0 19 0.074 0.194 View mutations
153 H 19 0 19 0.014 0.134 View mutations
154 Y 19 0 19 0.070 0.130 View mutations
155 V 16 3 19 0.212 0.357 View mutations
156 A 17 2 19 0.143 0.474 View mutations
157 A 19 0 19 0.041 0.353 View mutations
158 P 11 8 19 0.504 0.468 View mutations
159 R 15 4 19 0.210 0.427 View mutations
160 R 9 10 19 0.457 0.507 View mutations
161 M 18 1 19 0.065 0.336 View mutations
162 L 1 18 19 0.757 0.798 View mutations
163 G 18 1 19 0.078 0.349 View mutations
164 A 19 0 19 0.002 0.380 View mutations
165 P 15 4 19 0.339 0.286 View mutations
166 L 19 0 19 0.048 0.186 View mutations
167 R 19 0 19 0.018 0.271 View mutations
168 Q 19 0 19 0.004 0.362 View mutations
169 R 19 0 19 0.002 0.264 View mutations
170 R 19 0 19 0.009 0.339 View mutations
171 V 19 0 19 0.003 0.289 View mutations
172 R 19 0 19 0.001 0.272 View mutations
173 P 19 0 19 0.000 0.204 View mutations
174 L 19 0 19 0.005 0.082 View mutations
175 Q 19 0 19 0.009 0.096 View mutations