O43502 (O43502)

Overview
Predicted structure (AF):
AF-O43502-F1-model_v4
Uniprot entry:
O43502
Gene:
O43502
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4034 out of 7143 mutations
Pathogenic based on D2Deep prediction:
3109 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7143 mutations across 376 unique positions. There are 4034 benign and 3109 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 H 6 13 19 0.678 0.432 View mutations
277 R 18 1 19 0.063 0.467 View mutations
278 L 18 1 19 0.075 0.447 View mutations
279 A 0 19 19 0.951 0.638 View mutations
280 V 9 10 19 0.522 0.506 View mutations
281 I 2 17 19 0.915 0.548 View mutations
282 L 4 15 19 0.815 0.535 View mutations
283 T 1 18 19 0.896 0.658 View mutations
284 N 0 19 19 1.000 0.736 View mutations
285 Q 1 18 19 0.883 0.731 View mutations
286 M 7 12 19 0.596 0.549 View mutations
287 T 13 6 19 0.427 0.423 View mutations
288 T 3 16 19 0.751 0.600 View mutations
289 K 16 3 19 0.141 0.436 View mutations
290 I 10 9 19 0.513 0.439 View mutations
291 D 9 10 19 0.537 0.448 View mutations
292 R 14 5 19 0.314 0.532 View mutations
293 N 18 1 19 0.028 0.550 View mutations
294 Q 19 0 19 0.003 0.534 View mutations
295 A 19 0 19 0.001 0.446 View mutations
296 L 19 0 19 0.000 0.529 View mutations
297 L 10 9 19 0.510 0.494 View mutations
298 V 1 18 19 0.889 0.650 View mutations
299 P 0 19 19 1.000 0.820 View mutations
300 A 0 19 19 0.980 0.760 View mutations