O43502 (O43502)

Overview
Predicted structure (AF):
AF-O43502-F1-model_v4
Uniprot entry:
O43502
Gene:
O43502
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4034 out of 7143 mutations
Pathogenic based on D2Deep prediction:
3109 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4034 benign and 3109 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 A 19 0 19 0.028 0.933 View mutations
77 G 19 0 19 0.006 1.000 View mutations
78 T 11 8 19 0.392 0.565 View mutations
79 S 19 0 19 0.034 0.998 View mutations
80 E 18 1 19 0.119 0.899 View mutations
81 S 17 2 19 0.118 0.805 View mutations
82 H 19 0 19 0.004 0.879 View mutations
83 K 19 0 19 0.007 0.806 View mutations
84 K 19 0 19 0.005 0.665 View mutations
85 C 17 2 19 0.171 0.569 View mutations
86 T 13 6 19 0.296 0.479 View mutations
87 A 0 19 19 0.994 0.811 View mutations
88 L 4 15 19 0.764 0.635 View mutations
89 E 17 2 19 0.171 0.400 View mutations
90 L 18 1 19 0.112 0.325 View mutations
91 L 12 7 19 0.496 0.423 View mutations
92 E 19 0 19 0.000 0.393 View mutations
93 Q 18 1 19 0.080 0.402 View mutations
94 E 8 11 19 0.573 0.541 View mutations
95 H 8 11 19 0.580 0.510 View mutations
96 T 10 9 19 0.470 0.423 View mutations
97 Q 19 0 19 0.012 0.362 View mutations
98 G 18 1 19 0.083 0.488 View mutations
99 F 15 4 19 0.211 0.469 View mutations
100 I 11 8 19 0.386 0.469 View mutations