O43543 (XRCC2)

Overview
Predicted structure (AF):
AF-O43543-F1-model_v4
Uniprot entry:
O43543
Gene:
XRCC2
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
2575 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2744 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5319 mutations across 280 unique positions. There are 2575 benign and 2744 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.002 0.642 View mutations
2 C 19 0 19 0.063 0.808 View mutations
3 S 5 14 19 0.685 0.315 View mutations
4 A 19 0 19 0.011 0.818 View mutations
5 F 19 0 19 0.001 0.754 View mutations
6 H 19 0 19 0.003 0.785 View mutations
7 R 19 0 19 0.001 0.748 View mutations
8 A 19 0 19 0.001 0.680 View mutations
9 E 19 0 19 0.120 0.619 View mutations
10 S 12 7 19 0.357 0.517 View mutations
11 G 13 6 19 0.332 0.485 View mutations
12 T 10 9 19 0.473 0.471 View mutations
13 E 17 2 19 0.104 0.613 View mutations
14 L 4 15 19 0.810 0.460 View mutations
15 L 16 3 19 0.202 0.392 View mutations
16 A 18 1 19 0.032 0.385 View mutations
17 R 1 18 19 0.893 0.481 View mutations
18 L 0 19 19 0.994 0.615 View mutations
19 E 5 14 19 0.632 0.460 View mutations
20 G 6 13 19 0.654 0.522 View mutations
21 R 0 19 19 0.992 0.471 View mutations
22 S 9 10 19 0.548 0.440 View mutations
23 S 0 19 19 0.942 0.408 View mutations
24 L 3 16 19 0.815 0.416 View mutations
25 K 6 13 19 0.664 0.411 View mutations