O43543 (XRCC2)

Overview
Predicted structure (AF):
AF-O43543-F1-model_v4
Uniprot entry:
O43543
Gene:
XRCC2
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
2575 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2744 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5319 mutations across 280 unique positions. There are 2575 benign and 2744 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 G 0 19 19 0.986 0.571 View mutations
277 V 18 1 19 0.162 0.453 View mutations
278 E 15 4 19 0.206 0.410 View mutations
279 F 13 6 19 0.352 0.406 View mutations
280 C 14 5 19 0.386 0.458 View mutations