O43543 (XRCC2)

Overview
Predicted structure (AF):
AF-O43543-F1-model_v4
Uniprot entry:
O43543
Gene:
XRCC2
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
2575 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2744 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5319 mutations across 280 unique positions. There are 2575 benign and 2744 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 G 0 19 19 1.000 0.852 View mutations
52 T 0 19 19 0.995 0.745 View mutations
53 G 0 19 19 1.000 0.788 View mutations
54 K 0 19 19 1.000 0.770 View mutations
55 T 6 13 19 0.665 0.616 View mutations
56 E 0 19 19 0.997 0.754 View mutations
57 M 0 19 19 1.000 0.729 View mutations
58 L 0 19 19 0.978 0.574 View mutations
59 Y 2 17 19 0.880 0.658 View mutations
60 H 0 19 19 0.990 0.690 View mutations
61 L 1 18 19 0.927 0.606 View mutations
62 T 1 18 19 0.935 0.564 View mutations
63 A 5 14 19 0.736 0.545 View mutations
64 R 2 17 19 0.866 0.587 View mutations
65 C 0 19 19 0.987 0.680 View mutations
66 I 1 18 19 0.952 0.651 View mutations
67 L 2 17 19 0.878 0.521 View mutations
68 P 0 19 19 1.000 0.608 View mutations
69 K 15 4 19 0.223 0.434 View mutations
70 S 14 5 19 0.274 0.444 View mutations
71 E 10 9 19 0.473 0.429 View mutations
72 G 0 19 19 0.997 0.710 View mutations
73 G 0 19 19 1.000 0.779 View mutations
74 L 1 18 19 0.947 0.705 View mutations
75 E 1 18 19 0.936 0.564 View mutations