O43791 (O43791)

Overview
Predicted structure (AF):
AF-O43791-F1-model_v4
Uniprot entry:
O43791
Gene:
O43791
Protein length:
374 residues
Mutations found:
7105
Benign based on D2Deep prediction:
5199 out of 7105 mutations
Pathogenic based on D2Deep prediction:
1906 out of 7105 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7105 mutations across 374 unique positions. There are 5199 benign and 1906 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 A 0 19 19 0.997 0.734 View mutations
277 A 17 2 19 0.168 0.207 View mutations
278 D 19 0 19 0.002 0.251 View mutations
279 K 9 10 19 0.497 0.506 View mutations
280 Y 8 11 19 0.644 0.539 View mutations
281 A 4 15 19 0.826 0.542 View mutations
282 L 3 16 19 0.812 0.646 View mutations
283 E 4 15 19 0.751 0.546 View mutations
284 R 2 17 19 0.879 0.518 View mutations
285 L 1 18 19 0.950 0.819 View mutations
286 K 18 1 19 0.065 0.302 View mutations
287 V 17 2 19 0.092 0.322 View mutations
288 M 8 11 19 0.603 0.520 View mutations
289 C 19 0 19 0.000 0.178 View mutations
290 E 11 8 19 0.465 0.467 View mutations
291 D 11 8 19 0.415 0.428 View mutations
292 A 12 7 19 0.346 0.474 View mutations
293 L 19 0 19 0.000 0.303 View mutations
294 C 13 6 19 0.323 0.479 View mutations
295 S 19 0 19 0.000 0.494 View mutations
296 N 19 0 19 0.000 0.367 View mutations
297 L 6 13 19 0.704 0.586 View mutations
298 S 18 1 19 0.075 0.458 View mutations
299 V 12 7 19 0.353 0.462 View mutations
300 E 9 10 19 0.557 0.503 View mutations