O43791 (O43791)

Overview
Predicted structure (AF):
AF-O43791-F1-model_v4
Uniprot entry:
O43791
Gene:
O43791
Protein length:
374 residues
Mutations found:
7105
Benign based on D2Deep prediction:
5199 out of 7105 mutations
Pathogenic based on D2Deep prediction:
1906 out of 7105 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7105 mutations across 374 unique positions. There are 5199 benign and 1906 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 F 13 6 19 0.359 0.419 View mutations
252 K 16 3 19 0.222 0.506 View mutations
253 E 8 11 19 0.547 0.507 View mutations
254 M 19 0 19 0.002 0.236 View mutations
255 M 19 0 19 0.048 0.451 View mutations
256 C 18 1 19 0.082 0.483 View mutations
257 F 1 18 19 0.889 0.647 View mutations
258 I 13 6 19 0.344 0.421 View mutations
259 Y 8 11 19 0.638 0.557 View mutations
260 T 18 1 19 0.056 0.392 View mutations
261 G 2 17 19 0.847 0.625 View mutations
262 K 3 16 19 0.751 0.418 View mutations
263 A 19 0 19 0.071 0.384 View mutations
264 P 18 1 19 0.073 0.449 View mutations
265 N 19 0 19 0.007 0.484 View mutations
266 L 18 1 19 0.100 0.496 View mutations
267 D 18 1 19 0.081 0.513 View mutations
268 K 19 0 19 0.033 0.510 View mutations
269 M 16 3 19 0.156 0.383 View mutations
270 A 2 17 19 0.851 0.596 View mutations
271 D 12 7 19 0.361 0.445 View mutations
272 D 19 0 19 0.000 0.511 View mutations
273 L 8 11 19 0.597 0.511 View mutations
274 L 0 19 19 0.995 0.766 View mutations
275 A 19 0 19 0.003 0.443 View mutations