O43791 (O43791)

Overview
Predicted structure (AF):
AF-O43791-F1-model_v4
Uniprot entry:
O43791
Gene:
O43791
Protein length:
374 residues
Mutations found:
7105
Benign based on D2Deep prediction:
5199 out of 7105 mutations
Pathogenic based on D2Deep prediction:
1906 out of 7105 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7105 mutations across 374 unique positions. There are 5199 benign and 1906 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 Q 19 0 19 0.026 0.567 View mutations
27 I 19 0 19 0.029 0.530 View mutations
28 K 18 1 19 0.176 0.476 View mutations
29 V 18 1 19 0.129 0.475 View mutations
30 V 18 1 19 0.171 0.496 View mutations
31 K 19 0 19 0.010 0.498 View mutations
32 F 19 0 19 0.058 0.465 View mutations
33 S 8 11 19 0.591 0.433 View mutations
34 Y 16 3 19 0.152 0.418 View mutations
35 M 18 1 19 0.099 0.371 View mutations
36 W 5 14 19 0.678 0.583 View mutations
37 T 19 0 19 0.002 0.376 View mutations
38 I 1 18 19 0.967 0.820 View mutations
39 N 6 13 19 0.663 0.582 View mutations
40 N 14 5 19 0.324 0.372 View mutations
41 F 14 5 19 0.391 0.402 View mutations
42 S 19 0 19 0.004 0.373 View mutations
43 F 19 0 19 0.000 0.368 View mutations
44 C 18 1 19 0.124 0.432 View mutations
45 R 5 14 19 0.685 0.555 View mutations
46 E 13 6 19 0.255 0.447 View mutations
47 E 19 0 19 0.074 0.367 View mutations
48 M 19 0 19 0.008 0.490 View mutations
49 G 19 0 19 0.081 0.383 View mutations
50 E 2 17 19 0.828 0.517 View mutations