O43791 (O43791)

Overview
Predicted structure (AF):
AF-O43791-F1-model_v4
Uniprot entry:
O43791
Gene:
O43791
Protein length:
374 residues
Mutations found:
7105
Benign based on D2Deep prediction:
5199 out of 7105 mutations
Pathogenic based on D2Deep prediction:
1906 out of 7105 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7105 mutations across 374 unique positions. There are 5199 benign and 1906 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 L 7 12 19 0.566 0.538 View mutations
77 D 14 5 19 0.247 0.395 View mutations
78 E 1 18 19 0.948 0.739 View mutations
79 E 1 18 19 0.866 0.712 View mutations
80 S 1 18 19 0.945 0.827 View mutations
81 K 3 16 19 0.837 0.631 View mutations
82 D 1 18 19 0.949 0.791 View mutations
83 Y 1 18 19 0.944 0.803 View mutations
84 L 17 2 19 0.108 0.166 View mutations
85 S 0 19 19 0.995 0.960 View mutations
86 L 14 5 19 0.303 0.310 View mutations
87 Y 2 17 19 0.833 0.639 View mutations
88 L 2 17 19 0.885 0.838 View mutations
89 L 19 0 19 0.002 0.373 View mutations
90 L 19 0 19 0.005 0.026 View mutations
91 V 19 0 19 0.022 0.398 View mutations
92 S 19 0 19 0.000 0.332 View mutations
93 C 18 1 19 0.058 0.479 View mutations
94 P 19 0 19 0.000 0.373 View mutations
95 K 17 2 19 0.219 0.439 View mutations
96 S 10 9 19 0.519 0.487 View mutations
97 E 19 0 19 0.071 0.376 View mutations
98 V 18 1 19 0.117 0.231 View mutations
99 R 8 11 19 0.595 0.516 View mutations
100 A 1 18 19 0.886 0.789 View mutations