O43791 (O43791)

Overview
Predicted structure (AF):
AF-O43791-F1-model_v4
Uniprot entry:
O43791
Gene:
O43791
Protein length:
374 residues
Mutations found:
7105
Benign based on D2Deep prediction:
5199 out of 7105 mutations
Pathogenic based on D2Deep prediction:
1906 out of 7105 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7105 mutations across 374 unique positions. There are 5199 benign and 1906 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 V 7 12 19 0.685 0.436 View mutations
52 I 7 12 19 0.648 0.545 View mutations
53 K 2 17 19 0.880 0.518 View mutations
54 S 11 8 19 0.425 0.447 View mutations
55 S 19 0 19 0.000 0.217 View mutations
56 T 19 0 19 0.057 0.302 View mutations
57 F 1 18 19 0.919 0.772 View mutations
58 S 19 0 19 0.000 0.326 View mutations
59 S 19 0 19 0.009 0.377 View mutations
60 G 19 0 19 0.031 0.330 View mutations
61 A 19 0 19 0.071 0.460 View mutations
62 N 9 10 19 0.475 0.501 View mutations
63 D 18 1 19 0.118 0.432 View mutations
64 K 19 0 19 0.030 0.508 View mutations
65 L 18 1 19 0.090 0.536 View mutations
66 K 14 5 19 0.292 0.442 View mutations
67 W 0 19 19 0.984 0.623 View mutations
68 C 6 13 19 0.714 0.445 View mutations
69 L 18 1 19 0.098 0.243 View mutations
70 R 10 9 19 0.395 0.423 View mutations
71 V 4 15 19 0.782 0.587 View mutations
72 N 7 12 19 0.587 0.507 View mutations
73 P 0 19 19 0.999 0.748 View mutations
74 K 4 15 19 0.754 0.598 View mutations
75 G 3 16 19 0.759 0.772 View mutations