O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 12 6 18 0.343 0.441 View mutations
2 A 15 4 19 0.288 0.526 View mutations
3 T 9 10 19 0.492 0.448 View mutations
4 D 8 11 19 0.596 0.435 View mutations
5 A 17 2 19 0.097 0.556 View mutations
6 A 14 5 19 0.282 0.502 View mutations
7 L 11 8 19 0.448 0.415 View mutations
8 R 10 9 19 0.508 0.499 View mutations
9 R 7 12 19 0.607 0.443 View mutations
10 L 3 16 19 0.826 0.566 View mutations
11 L 10 9 19 0.424 0.491 View mutations
12 R 2 17 19 0.899 0.604 View mutations
13 L 7 12 19 0.640 0.535 View mutations
14 H 1 18 19 0.952 0.623 View mutations
15 R 4 15 19 0.760 0.646 View mutations
16 T 19 0 19 0.003 0.250 View mutations
17 E 2 17 19 0.893 0.705 View mutations
18 I 0 19 19 1.000 0.751 View mutations
19 A 2 17 19 0.842 0.657 View mutations
20 V 16 3 19 0.220 0.340 View mutations
21 A 0 19 19 1.000 0.708 View mutations
22 V 2 17 19 0.869 0.669 View mutations
23 D 0 19 19 0.992 0.722 View mutations
24 S 4 15 19 0.776 0.596 View mutations
25 A 0 19 19 1.000 0.734 View mutations