O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 F 4 15 19 0.749 0.664 View mutations
27 P 0 19 19 0.983 0.833 View mutations
28 L 2 17 19 0.915 0.720 View mutations
29 L 0 19 19 0.966 0.716 View mutations
30 H 3 16 19 0.814 0.688 View mutations
31 A 10 9 19 0.413 0.488 View mutations
32 L 1 18 19 0.949 0.766 View mutations
33 A 1 18 19 0.935 0.707 View mutations
34 D 3 16 19 0.810 0.694 View mutations
35 H 0 19 19 0.996 0.638 View mutations
36 D 14 5 19 0.257 0.410 View mutations
37 V 4 15 19 0.779 0.618 View mutations
38 V 1 18 19 0.948 0.655 View mutations
39 P 1 18 19 0.956 0.642 View mutations
40 E 2 17 19 0.920 0.650 View mutations
41 D 1 18 19 0.946 0.578 View mutations
42 K 4 15 19 0.748 0.537 View mutations
43 F 7 12 19 0.605 0.536 View mutations
44 Q 1 18 19 0.927 0.609 View mutations
45 E 0 19 19 0.977 0.695 View mutations
46 T 7 12 19 0.680 0.560 View mutations
47 L 9 10 19 0.532 0.508 View mutations
48 H 10 9 19 0.486 0.495 View mutations
49 L 7 12 19 0.685 0.557 View mutations
50 K 1 18 19 0.965 0.606 View mutations