O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 E 1 18 19 0.950 0.666 View mutations
52 K 3 16 19 0.830 0.556 View mutations
53 E 1 18 19 0.956 0.651 View mutations
54 G 0 19 19 0.996 0.743 View mutations
55 C 18 1 19 0.082 0.327 View mutations
56 P 4 15 19 0.769 0.637 View mutations
57 Q 2 17 19 0.943 0.629 View mutations
58 A 2 17 19 0.919 0.756 View mutations
59 F 1 18 19 0.920 0.734 View mutations
60 H 2 17 19 0.769 0.694 View mutations
61 A 2 17 19 0.921 0.758 View mutations
62 L 0 19 19 1.000 0.853 View mutations
63 L 5 14 19 0.761 0.650 View mutations
64 S 9 10 19 0.539 0.521 View mutations
65 W 0 19 19 1.000 0.820 View mutations
66 L 0 19 19 0.979 0.926 View mutations
67 L 1 18 19 0.949 0.804 View mutations
68 T 3 16 19 0.778 0.676 View mutations
69 Q 7 12 19 0.632 0.558 View mutations
70 D 6 13 19 0.659 0.573 View mutations
71 S 6 13 19 0.622 0.532 View mutations
72 T 17 2 19 0.203 0.425 View mutations
73 A 3 16 19 0.808 0.618 View mutations
74 I 1 18 19 0.950 0.809 View mutations
75 L 8 11 19 0.655 0.526 View mutations