O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
526 D 6 13 19 0.607 0.559 View mutations
527 G 19 0 19 0.000 0.329 View mutations
528 I 14 5 19 0.238 0.460 View mutations
529 L 16 3 19 0.205 0.415 View mutations
530 Q 1 18 19 0.940 0.598 View mutations
531 W 0 19 19 0.986 0.638 View mutations
532 A 0 19 19 0.987 0.646 View mutations
533 I 2 17 19 0.857 0.610 View mutations
534 Q 0 19 19 1.000 0.566 View mutations
535 S 4 15 19 0.805 0.590 View mutations
536 M 7 12 19 0.558 0.532 View mutations
537 A 15 4 19 0.204 0.426 View mutations
538 R 0 19 19 0.985 0.520 View mutations
539 P 13 6 19 0.310 0.453 View mutations
540 A 17 2 19 0.094 0.446 View mutations
541 A 13 6 19 0.345 0.398 View mutations
542 P 16 3 19 0.151 0.407 View mutations
543 F 10 9 19 0.477 0.432 View mutations
544 P 10 9 19 0.475 0.440 View mutations
545 S 17 2 19 0.114 0.582 View mutations